Side Effects

From mental health to public health and everything in-between

Christopher Lane Ph.D.

Protracted Withdrawal Syndrome After Antidepressant Use

Withdrawal from widely prescribed drugs is common but mostly unstudied.

The Link Between Payments and Prescribing

A systematic review finds a clear and consistent association between drug company payments and physician prescribing.

Medicating Normal: A Film Review

A compelling new documentary weighs the toll of overprescribing.

“Chemically Imbalanced”

A leading sociologist examines how Americans think about medication and everyday suffering.

Outcome Switching and Withheld Data in COVID-19 Research

Concern mounts about misleading data.

Antidepressants and Online Misinformation

A study of medical websites finds widespread misreporting.

A Health Crisis and Herd Immunity

Lessons from Britain’s disastrous coronavirus response.

The Push to Rethink Psychiatric Diagnosis

A major new initiative to change how we approach and treat mental distress.

The Disturbing Rise in Benzodiazepine Prescriptions

Are benzodiazepines helping to fuel the opioid crisis?

Esketamine and the Search for New Ways to Treat Depression

Re-analysis of FDA data raises questions about the drug’s safety and effectiveness.

The Truth About Medical PR

A textbook case on medical ethics.

Antidepressants and Major Depressive Disorder

New studies show minimal improvement over placebo but continued risk of harm.

Antidepressant Withdrawal and Scientific Consensus

Why did academic psychiatry take two decades to recognize the condition?

The Day My Medical Data Was Hacked

Are data breaches becoming a new normal?

Post-SSRI Sexual Dysfunction Recognized as Medical Condition

European regulators recognize a medical condition. Will their U.S. counterparts?

Antidepressant Guidelines to Tighten in the UK

Prescribing guidelines for antidepressants are about to be tightened in the UK. Why the changes? And why did they take decades to implement?

Can a New Medical Device Help Treat ADHD?

The FDA recently approved a medical device to treat ADHD. But does it actually modify behavior—and was the single study leading to its approval sufficiently rigorous?

On the Biology of Mental Disorders

A major new study questions whether mental disorders are brain disorders.

Our Psychiatric Future

A compelling, vitally important new book lays out the controversies facing those in mental health and proposes how best to resolve them.

Antipsychotics Tied to Higher Risk of Death in Children

A large new study finds an increased risk of unexpected deaths in patients aged 5 to 24 who received antipsychotics.

Antidepressant Withdrawal and Patient Safety

A new survey of withdrawal from psychiatric drugs points to symptoms that are often incapacitating but poorly understood by those prescribing.

Antidepressant Withdrawal Said to Affect “Millions”

A major new study finds that antidepressant withdrawal is much more widespread, chronic, and longer-lasting than national guidelines suggest.

Digital Health and the Rise of Mental Health Apps

New research warns that self-diagnosing apps are unreliable and encourage overtreatment.

As Child Anxiety Rises, Effective Treatment Proves Elusive

With child and teen anxiety on the rise, new research shows that preferred treatments often have poor long-term outcomes.

National Well-Being and Rates of Depression

Our well-being and that of our neighbors is more interlinked than we realize.

Flaws in the Algo: How Social Media Fuel Political Extremism

New research documents just how forcefully social media algorithms are driving polarization.

How “Manipulation Armies” Are Undermining Democracies

A new report on the closed loops of disinformation stoking chaos and confusion.

ADHD Is Now Widely Overdiagnosed and for Multiple Reasons

In the U.S. and other developed countries, there are now clear signs that child and adolescent mental disorders are overdiagnosed.

The U.S. Is Not Doing Well Socially

The U.S. shows growing signs of being an unhappy, divided country, according to a string of indexes measuring national happiness and well-being.

The Gene Machine: An Interview with Bonnie Rochman

The expanding influence of genomics on our lives.

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