Can Skincare Influence Your Brain and Mood?

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The science of cosmetics is reshaping how we view skincare—not just as a way to improve appearance but as a means to support emotional well-being (Seo, 2024). New research explores the connections between the skin, brain, and nervous system.

Our skin is far more than just a protective barrier. It’s a highly sensitive organ filled with nerve endings, neurotransmitter receptors, and immune cells that interact with our brain. When we experience stress, for example, it can trigger skin problems like inflammation or acne due to the release of cortisol (Garg and colleagues, 2019). Conversely, soothing the skin can help reduce stress signals and improve mood through targeted skin-brain pathways.

Skincare products are formulated with ingredients that interact with the skin’s sensory and nervous systems to influence emotional and physical responses. These formulations target the skin-brain axis—a pathway through which external stimuli on the skin can affect brain chemistry and stress regulation (Liao and colleagues, 2022).

This is unlike traditional skincare, which focuses solely on hydration or anti-aging. Instead, the focus is on:

• Regulate stress by reducing cortisol production.
• Promote mood-lifting neurotransmitters like serotonin and dopamine.
• Soothe the nervous system, enhancing emotional well-being.

The effectiveness lies in the science of psychodermatology, which studies the relationship between mental states and skin health.

1. The Influence on Cortisol and Stress
   Skincare ingredients like botanical extracts (lavender, chamomile) and peptides can help reduce cortisol levels. Liao and colleagues (2022) found that active ingredients, like certain peptides, could block stress signals in the skin, leading to reduced inflammation and improved resilience.
2. Influence on Neurotransmitters
   Some ingredients directly stimulate the release of serotonin and dopamine—neurotransmitters that regulate mood and happiness. For example, essential oils such as lavender and bergamot have been shown to calm the nervous system and promote relaxation (Goes et al., 2012).
3. Sensory Stimulation:
   The experience of such products—like the gentle touch involved in massaging creams or serums—activates the brain’s sensory pathways. This tactile stimulation can trigger the release of oxytocin, a hormone associated with bonding and relaxation, as well as endorphins, which reduce pain and boost pleasure (Field and colleagues, 2021).

Why Skincare and Brain Health Are Connected

In a previous post, I discussed the concept of the gut-skin-brain axis, highlighting the interconnection of our physical and emotional states. Stress and poor mental health can disrupt the skin barrier, weaken immunity, and worsen skin conditions like eczema and acne (Garg and colleagues, 2019). By reducing stress and soothing the skin, psychodermatology offers a two-way benefit of healthier skin and improved mental well-being. For example, self-care routines incorporating skincare help reduce stress and improve emotional regulation. Such rituals provide structure, mindfulness, and a moment of calm—critical for mental health.

Here are some ingredients to look for:

• Lavender and Chamomile: Natural relaxants shown to reduce anxiety and improve sleep (Goesand colleagues, 2012)
• Niacinamide: Known for reducing inflammation and supporting skin barrier function, which also helps lower systemic stress (Zhou and colleagues, 2023).
• Peptides: Certain bioactive peptides can calm the skin and block stress-related inflammatory pathways (Liao and colleagues (2022).
• Probiotics: Emerging evidence suggests that topically applied probiotics can balance the skin microbiome, which indirectly reduces stress and inflammation (Biedermann and colleagues, 2015).

The Future of Psychodermatology

A growing popularity reflects a broader cultural shift toward self-care and holistic health. Skincare is no longer just about vanity; it’s about emotional wellness. Researchers continue to explore how active formulations can be optimized to reduce stress, improve emotional balance, and offer targeted support for both the mind and body.

Copyright 2024 Tara Well