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Charles Zorumski M.D., Eugene Rubin M.D., Ph.D.
Depressive disorders are not caused by serotonin dysfunction. Many neurotransmitters influence the neural networks underlying depressive symptoms.
About 15 to 20 percent of individuals experience psychiatric and/or neurological symptoms in the 12 months following recovery from COVID-19. Here's what we know.
A new research definition of recovery from alcohol use disorder (AUD) has two components: (1) no longer fulfilling the DSM-5 criteria for AUD and (2) refraining from heavy drinking.
A recent study provides evidence that people with a history of psychiatric disorders are at increased risk for developing dementia later in life.
Collaborative models may offer a cost-effective method of psychiatric care for many patients.
A small, well-designed study suggests that esmethadone has significant and rapid antidepressant properties that continue after the drug is discontinued.
Individuals fall into one of four patterns of depressive symptoms following a major stressor. Genetics may help predict which pattern an individual will follow.
Cognitive behavioral therapy is an effective treatment for insomnia. In a recent study, it led to both improvement in insomnia and reduction in risk for developing depression.
Individuals with obsessive-compulsive disorder may have increased risk of developing dementia, including Alzheimer’s disease and vascular dementia, later in life.
Psychotic disorders and mood disorders are associated with an increased risk of dying from COVID-19, new research finds; anxiety disorders are not.
A recent study demonstrated that an oral form of a neuroactive steroid may be an effective treatment for combating symptoms of postpartum depression.
Investigators recently developed parallel methods to study hallucination-like perceptions in humans and in mice.
Higher trait anxiety in mothers correlates with increased responsiveness to unfamiliar noise bursts in specific brain regions of 4-week-old infants.
Forty percent of patients with severe, treatment-resistant depression experienced remission of symptoms two weeks after a single, one-hour inhalation of nitrous oxide.
A history of mood disorders is associated with increased death rates and a decreased likelihood of discharge home for patients hospitalized for COVID-19.
Drugs used to treat schizophrenia are also effective in bipolar disorder. With advances in understanding of psychiatric illnesses, it may be becoming clearer why this is so.
To reach the large number of individuals suffering from depression and anxiety, health care models are being implemented where psychiatrists advise primary care teams.
A recent study investigated the efficacy of deep brain stimulation for severe, treatment-refractory OCD. Over half of the participants in this study showed significant improvement.
There is a striking relationship between a history of psychiatric symptoms and the rate of aging. This relationship is clearly evident by age 45.
Although traumatic brain injury (TBI) involves brain-related symptoms, other organs including the immune system, GI system, lungs, and heart also may become compromised.
A recent paper reported that 1.7 percent of persons with schizophrenia spectrum disorders died by suicide. About half did so within five years of first diagnosis.
Although psychotic symptoms are often the most dramatic and visible features of schizophrenia, other symptoms are likely responsible for poor long-term outcomes.
Neurosurgical ablation of a specific brain area led to marked improvement in two patients suffering from both treatment-refractory epilepsy and treatment-resistant PTSD.
Two reports indicate that a single intravenous infusion of ketamine can help reduce alcohol consumption in people with problematic drinking behaviors.
The mental health consequences of the pandemic have been dramatic, and young adults are especially susceptible to anxiety and depressive symptoms.
Although the virus causing COVID-19 can directly affect the brain, psychiatric symptoms resulting from pandemic-related stressors are much more common.
Major progress is being made in developing blood tests to detect Alzheimer’s disease even in pre-symptomatic phases. This is important for several reasons.
The intersection of the COVID-19 pandemic and Black Lives Matter movement is stimulating much needed discussion and action about diversity and equity at academic medical centers.
COVID-19 can cause brain-related complications, including new-onset psychosis and strokes.
In two longitudinal studies, there was a strong association between attendance at religious services and fewer deaths related to suicide, drugs, and alcohol.
Charles F. Zorumski, MD, is Samuel B. Guze Professor and Head of Psychiatry at Washington University in St. Louis - School of Medicine.
Eugene Rubin, M.D., Ph.D., is Professor Emeritus in the Department of Psychiatry at Washington University School of Medicine in St. Louis.