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Ten Ways to Slow Mental Decline with Age

Start early and enjoy a sharp mind in your old age.

Deterioration of the brain usually sneaks up on us. By the time we realize it, it may be too late. As we get older, we more frequently start asking questions like “Where did I put the car keys?” “What was it I was supposed to get at the store?” “What’s your name again?” Most of us seniors have had to ask questions like this, and it seems to happen more often as we get older. We can’t turn back our biological clock, but there are things seniors can do to reduce the rate of their mental decline. The time to act is while you are still relatively young.

I have made a career out of studying the brain and behavioral research literature, and I know some of this research is relevant to everyday memory problems. I have learned that as people age, beginning in early middle age, many of them experience a brain deterioration that progresses silently over the next decade or two, sometimes ending in devastating senility. Behaviorally, aging can cause your reflexes to slow. You walk and act slower. You even talk slower. Our memory starts to fail, especially the short-term form of memory ability that is so crucial for learning new things.

Now that brain-scan technology is widely available, physicians have discovered that the brain usually shrinks as people get older. The shrinkage increases the space between the brain surface and the skull. The cavities that hold cerebrospinal fluid get bigger. Nerve tracts in the brain shrivel, even leaving gaping holes in the brain. The “dendritic trees” shrivel, and these have major consequences because dendrites are the parts of neurons that form the contact points, and their loss reduces brain circuitry. You may also lose 40% or more of your dopamine neurons, and that may lead to Parkinson’s disease

For aging individuals, the challenge is to reduce the rate of their decline. This has created a growth anti-aging industry focused on vitamins and anti-oxidant supplements, fad diets, gym facilities, mind training programs. The good news is that some of these things work if they are begun while people are in early middle age. Given that our country now has so many baby boomers in the over-50 category, it seems useful to summarize some things people can do to prevent or slow memory decline as they age.

Here is a list of 10 things I think are especially important for people entering middle age.

1. Get better organized. Many things we try to remember do not have to be remembered if we get better organized. Car keys, for example, should ONLY be in the car if you are driving it, in your pocket/purse, or the same place in your house. Ditto for many other objects, such as a purse, hat, glasses, etc. Life is a lot simpler when you have a place for everything, with everything in its place. Habit relieves the memory.

2. Make a special effort to pay attention, concentrate. Research shows that aging reduces a person’s ability to focus and pay attention. This also means that seniors have to work harder at filtering distractions, such as when we open the refrigerator door and forget what we are looking for because we thought of something else before we opened the door. New learning has to be consolidated to form lasting memory, and this takes a little uninterrupted time and conscious rehearsal right after you learn it. Seniors are especially susceptible to having temporary memories wiped out by distractions.

3. Challenge yourself mentally. Seek out new experiences, an active social life, and mental demands such as learning a new language, playing chess, or getting an advanced college degree. Learning new things can have the benefit of making you feel good about yourself, and this is especially true for seniors who accomplish things most people think they can’t do. By the way, there is abundant research literature showing that a lifetime of vigorous learning helps stave off Alzheimer’s disease.

4. Reduce Stress. Acute stress helps you be alert, pay attention better, and increase your chances of remembering what is happening at the time of stress. But chronic stress, whether caused by the same or different stressors, clearly disrupts memory formation and recall. Chronic stress and the hormones it releases shrink synapses and can actually kill neurons and shrink the brain (which shrinks with age anyway and only gets worse with chronic stress).

5. Eat foods with vitamins and anti-oxidants. Make certain you have a balanced diet. Supplements usually won’t help memory unless you have a nutritional deficiency. But even with a good diet, adding vitamins C, D, and E can be helpful. Several research studies indicate a memory benefit from eating foods loaded with antioxidants, such as dark-colored berries, like blueberries (especially on an empty stomach). Another potent anti-oxidant is an ingredient in red wine, resveratrol, but there is no way you could drink enough; however, resveratrol supplements are now on the market. Anti-oxidant properties are found with curcumin and melatonin. There is also suggestive evidence for memory improvement from omega-3 fatty acids and folic acid.

Pharmaceuticals to improve memory are in the works, but you may have to wait quite a while before research shows which ones really work.

6. Don’t get obese, especially in middle age.

Confocal microscopy reveals that every added pound of fat adds approximately one mile of capillary tubing. Obviously, all these added vascular tubings put a strain on the heart. A diet that produces new fat may well contribute to hardening of the arteries, which in turn compounds the added workload on the heart. People who are obese commonly have high blood pressure and other risk factors involving metabolism.

Obesity is a common cause of diabetes, which adds its own toll on blood vessels and the heart, as well as on nerve cells. No wonder then that obese people may develop mental deterioration. The problem may be worse in women. The more a woman weighs, the worse her memory. No, I am not a chauvinist pig. This claim comes from actual research —by a woman, no less. Diana Kerwin and her colleagues at Northwestern University studied 8,745, ages 65 to 79 and found that for every one-point increase in body mass index, the score on a 100 point memory test dropped by one point.

A likely cause of mental decline in most people is diminished flow in small vessels that are easily plugged by cholesterol and lipids or ruptured by high blood pressure. These “mini-strokes” are probably quite common as we age, and though they go undetected, they cause cumulative damage that progressively affects our behavioral and mental capabilities. Brain cells are among the most metabolically active of all cells: they constantly fire electrical pulses and secrete relatively huge amounts of secretions (neurotransmitters). The brain consumes about 20% of all the body’s oxygen, even though it only ways about 3.5 pounds.

When brain cells do die or are damaged for any reason, healthy neurons are assaulted by inflammatory chemicals, like cytokines, that are released by the brain’s immune cell system. Fat deposits not only stress the heart, but they also increase the number of cytokines, which are hormones that can cause inflammation. Brain inflammation is also commonly caused by infections such as colds and flu and by diets deficient in anti-oxidants.

7. Exercise the body. Though exercise doesn’t do much to cause weight loss unless you are a marathon runner or tennis singles champion, it has many other benefits (improved circulation of blood to the brain, improved levels of HDL cholesterol) that can directly benefit memory and cognitive function. Vigorous aerobic exercise can improve your circulation and perhaps blood flow in the brain. But there also seem to be memory benefits from exercise that is independent of blood circulation. We don’t know why. Maybe relief of stress and improved mood are factors. We know that positive emotions help memory, but for unknown reasons.

8. Exercise the memory. The more you make an effort to memorize, the easier it seems to get. Practice the memorization tricks used by “memory athletes” that I describe in my books. I describe specific image-based systems (“peg systems”) for performing astonishing memory feats, such as card counting, remembering long strings of numbers, and remembering the gist of what is on every page of a magazine or book.

9. Get plenty of sleep. Many studies show the brain is processing the day’s events while you sleep and consolidating them in memory. This kind of “off-line” rehearsal occurs just for the learning experiences on the day of sleep. Naps help too! How’s that for good news?

10. Believe in your brain’s ability to get better. Of course, good genes and luck have a lot to do with how well one ages mentally. But good genes and luck seem to be more common in people who do the nine things mentioned above. Too many seniors buy into the popular myth that old dogs can’t learn new tricks. They resign themselves to defeatism. But the bottom line is that, unless you have Alzheimer’s disease, you can improve your mental sharpness. Getting older has enough frustrations. Don’t compound them by tolerating mental decline. Enjoy an improved brain.

Learn more about Dr. Klemm's ideas, writings, and activities at his web site, ( and his Improve Learning and Memory blog site (


Klemm, W. R. Improve Your Memory for a Healthy Brain. Memory Is the Canary in Your Brain's Coal Mine.