Stress generally refers to two things: the psychological perception of pressure, on the one hand, and the body's response to it, on the other, which involves multiple systems, from metabolism to muscles to memory. The response to stress is not just widespread, affecting almost all systems of the body and brain, but it is automatic, triggered by any perceived threat or demand that exceeds a person's ability to cope.

The automatic response system set off by the perception of threat is activated through hormonal signals. It is designed to instantly prepare an animal to meet a threat head-on or to flee from it—the fight-or-flight response..

Some stress is necessary for all living systems; it is the means by which they encounter and respond to the challenges and uncertainties of existence. Short-term, moderate doses of stress increase alertness, boost immunity, and spur brain growth.

What Causes Stress?

The perception of threat—whether it’s the sudden appearance of a snake on the path or the fear of losing your job when the boss yells—triggers a cascade of hormones, including adrenaline (epinephrine), noradrenaline (norepinephrine), and cortisol, that surge through the body.

The hormones increase heartbeat and the circulation of blood to support quick action, mobilize fat and sugar for immediate energy, focus attention to track the danger, prepare muscles for movement, and more.

This response was meant to be lifesaving under the condition in which early humans evolved. It solves short-term, life-threatening problems, such as the sudden appearance of a tiger. It was not meant for the extended difficulties of modern life, such as daily traffic jams and marital problems, to name just a few of the many challenges that can activate the stress response. The physiologic changes that underlies the potentially lifesaving fight-or-flight response are, if sustained, harmful to many systems of the body.

How to Manage Stress

There are both physical and psychological approaches to blunt stress. Physical steps include meditation, yoga, and exercise. Psychological strategies include leaning on loved ones or, in more severe cases, seeing a mental health professional.

Since the stress response begins in the brain with the perception of danger or the unknown, researchers now believe that the most basic, and likely most effective, way to diffuse stress is to change the perception of certain situations so that they are not seen as threatening in the first place.

Studies show that helping people see certain experiences—such as final exams—as demanding rather than dire protects them from the corrosive effects of stress while still delivering its positive effects, such as focused attention and speedier information processing. Changing the stress mindset not only minimizes the harms of stress, studies show, but it also enhances performance and productivity.

How Stress Affects Your Health

Short bursts of stress aren’t inherently harmful, although it can take time for the body to calm down. Yet prolonged or repeated arousal of the stress response can have harmful physical and psychological consequences. The repercussions include ailments from heart disease and diabetes to anxiety and depression.

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