I love the idea that what we do with our brains-- how we engage and take care of them-- can lead to improvements in how they function. I'm clearly not alone in this love affair, given the rapid growth of puzzles and easy-to-use video games that promise to enhance cognitive functioning. A large study appearing this month in the prestigious journal Nature, however, suggests that such quests for optimizing brain power may all be in vain. Ultimately, when it comes to building a better brain, a few video games probably won't do too much. If you really want to make some changes, it's probably time to stop playing games and start taking a more serious approach.