Parental Age & Mental Illness: The Maternal Dimension

The biggest and most comprehensive study of the effects of parental age on offspring mental illness confirms counter-tuitive predictions of the imprinted brain theory.

A New Science of Human Evolution—and Evolutionary Psychiatry

A new book highlights the revolution sweeping through evolution thanks to genomics and sets a precedent that the imprinted brain theory has already followed.

The Mothers of Mankind

Proposed self-domestication of our species raises the issue of who the domesticators were. Insights of the imprinted brain theory argue they were ancestral mothers.

Schizophrenics as Hyper-domesticated Humans

As predicted by the diametric model of mental illness, if autistics are hypo-domesticated, schizophrenics are hyper-domesticated.

Autistics as Undomesticated Humans

To the extent that humans are a self-domesticated species, autistics can be seen as less domesticated than others.

Key Brain Protein Has Implications for Psychiatric Disorders

Levels of the key brain protein, BDNF, vary as predicted by the diametric model of mental illness: lower in psychotic spectrum disorders, but higher in autistic spectrum ones.

Mothers, Madness, and Mitochondria

The role of mitochondria in providing energy and countering cancer, along with their maternal mode of inheritance, makes them predictably implicated in psychiatric disorders.

DNA Imaging: Icon of a New, Genomic Literacy

Images of DNA pose the problem of genomic literacy and raise questions about what the text of the genome means, with potentially revolutionary implications for society.

Now You See It: Diametric Differences Revealed in the Brain

The first study to image brain activity in game playing according to participants’ autistic as opposed to psychotic tendencies reveals patterns consistent with the diametric model.

My Experience of Psychosis

Transient post-operative delirium in critical care produced symptoms uniquely explained by the diametric model of mental illness.

Autistic vs. Psychotic Spectrums: Overlapping or Opposite?

The first study to consider both cognitive modes proposed by the diametric model finds evidence of overlap and diametric opposition of autistic as opposed to psychotic traits.

How to Win a Turing Tournament

Both a computer's mentalistic deficits and mechanistic over-compensations could be masked in a Turing test by having it masquerade as a savant like the late Kim Peek.

The Autism of Rodin’s Thinker

Autistic deficits in quick, intuitive social responses are balanced by strengths in more deliberative, objective, and unbiased reasoning, just as the diametric model implies.

Imagination and the Diametric Model of Mental Illness

Imagination is the facet of autism that best accounts for its male-biased sex ratio, and higher genetic risk of schizophrenia is associated with enhanced imagination.

Reading Asperger in the 'Reading the Mind in the Eyes' Test

An important precedent for our understanding of autism and its history is set by the finding that only a minority of autistics show an impairment on reading the mind in the eyes.

How Microbes, Viruses, Imprinted Genes, etc. Shape Behaviour

Important insights into mental health—not to mention into who we are—follow from the realization that biologically speaking human beings are anything but single, unified organisms.

Copy Number, Schizophrenia, and Autism: New Findings

Copy number of a DNA domain involved in brain development correlates with the symptoms of schizophrenia and with autism as predicted by the diametric model.

The Aliens Have Landed!

Many autistics feel like visitors from another planet, and the metaphor is a good one.

Beyond the "Selfie" Self: the Diametric View

Robert Trivers’ neo-Freudian view of the self-deceiving self is self-contradictory, but the diametric model suggests a more honest alternative.

Brain Organoids Show Predicted Epigenetic Effects in Autism

New evidence from cultured brain cells of autistics shows that over-expression of a brain growth gene is critical, just as predicted by the imprinted brain theory.

Reviewing the Evidence for Mental Illness Being Epigenetic

The basic claim of the imprinted brain theory that gene expression is critical in neuro-development is vindicated by a new review of the data.

Reading Too Much Into the Real Face Book

We know that autistics have deficits in interpreting facial expression, but now we also know that, as predicted by the diametric model, people with schizotypal traits do the opposite and exaggerate facial expression.

The X Factor: Genetics and Female Mental Health

XIST, the gene that controls X chromosome gene expression, is up regulated in psychosis, just as the imprinted brain theory predicts.

Testing the “Extreme Female Brain” Theory of Psychosis

The “extreme female brain” theory is added to the extreme male one of autism, but both add up to much less than the imprinted brain theory.

The Real Turing Test: Curing Computer Autism

People would accept that machines could think if a mentalistic user-interface could be engineered to give computers the skills that autistics lack.

Diametric Mentalizing Imaged in Autistic & Psychotic Brains

As predicted by the diametric model, brain scanning reveals hyper-active mentalism in schizophrenics but the opposite in autistics.

Lobotomy Cuts Both Ways (Diametrically Speaking)!

A patient cured of epilepsy by brain surgery acquired hyper-mentalistic symptoms as implied by the diametric model and predicted by the imprinted brain theory.

Diametric Differences in Seeing the Other’s Point of View

Both tendencies to autism and proneness to psychosis induce perspective-taking errors, but their interaction reduces these errors: a finding only explicable by the diametric model.

Beyond the Divided Self: Why Mental Conflict Is Normal

Although inner conflict has traditionally been pathologized, the diametric model shows it to be normal.

The Hand that Rocks the Cradle Rules—But Whose Hand Is It?

The history of the nature/nurture controversy reveals fraud on the nurture side and developments in our view of nature that the imprinted brain theory readily explains.