Long-Term Effects of Antipsychotics

Data support the long-term use of antipsychotics in persons with schizophrenia. However, less is known about the efficacy of long-term use for other conditions.

Head Injuries and Psychiatric Symptoms in Football Players

Over 40 percent of ex-football players with chronic traumatic encephalopathy exhibited behavioral changes.

Examining Functional Activity in an Individual’s Brain

Neuroimaging studies show that specific brain regions work together to accomplish specific tasks. Methods to analyze data for individual people may lead to personalized treatments.

Trends in the Treatment of Psychiatric Illnesses

The delivery of mental health care is changing in response to increased recognition of mental illness together with a decrease in the number of practicing psychiatrists.

Is Smoking Marijuana During Pregnancy Harmful?

Recent research demonstrates significant changes in the brains of developing fetuses as a result of marijuana exposure during pregnancy.

A Possible New Treatment for Post-Partum Depression

A neuroactive steroid whose levels increase dramatically during pregnancy and then fall rapidly after delivery is reported to be effective in treating post-partum depression.

“Memory Athletes” and the Rest of Us

With a specific type of memory training, individuals can alter connections within and between brain networks to resemble connections found in the brains of elite memory athletes.

Income, Education, Social Support, and Brain Development

Several studies have found adverse relationships among poverty, low parental educational levels, and brain development.

Pregnancy Causes Changes in Brain Structure

Specific brain regions change in volume when a woman becomes pregnant. These areas are associated with skills that may help a mother better understand the needs of her baby.

Treating Depression by Training Your Amygdala

A recent study indicates that increasing activity in the amygdala during positive memory retrieval can have a strong antidepressant effect in depressed individuals.

The Use of Ketamine as an Antidepressant

Little is known about the effectiveness or safety of repeated use of ketamine in treating depression. Recent recommendations urge caution.

Generation X Uses Mental Health Care Services Differently

Changes in the use of psychotropic medications during a 5 year interval varied among individuals in different generational cohorts.

Self-Injury Mortality: A Deadly Crisis

The number of deaths resulting from self-injury is staggering and growing. Over 70% of these deaths occur in people less than 55 years old.

Can Craving for Cocaine Be Blocked in Addicted Individuals?

Ketamine may significantly diminish craving for cocaine in addicted individuals.

Age-Related Mortality Associated with Alcohol Use Disorder

Alcohol use disorder is associated with a 5.8-fold increase in mortality rates. The reasons for this increase differ for younger and older individuals.

Intensive Treatment for Persistent Depression

A recent study compared 12 to 15 months of intensive specialized treatment to routine psychiatric care for patients with persistent depression.

Early-Life Environment Influences Brain Growth and Behavior

Two recent studies demonstrate that environment influences brain growth and emotional behavior in children and adolescents.

Misuse of Stimulants by College Students

Nonmedical use of prescription stimulants by college students is common. Students who misuse these drugs have a higher prevalence of alcohol use disorder and conduct disorder.

A Return of Psychedelic Medications?

Recently, there has been increased interest in the use of psychedelic drugs for the treatment of addictions and other psychiatric disorders.

How the Immune System Influences Suicidality

Many biological and environmental factors contribute to suicidal behaviors. Factors that stimulate the brain’s immune responses may increase the risk of suicide.

The Immune System and Psychiatry

Recent evidence demonstrates that the immune system plays a central role in regulating brain function.

One Step Closer to a Rapidly Acting Antidepressant?

Ketamine can rapidly reverse depressive symptoms, but it can have serious side effects. A metabolite of ketamine may be as effective and have fewer side effects.

A Possible New Class of Antidepressants

Recent advances in knowledge about the generation of new brain cells throughout the lifespan are leading to the development of new drugs to treat neuropsychiatric illnesses.

Cognitive Impairment in Depression

Cognitive symptoms of depression may not respond well to treatment with antidepressant medications.

Three Phases of Addiction

Strong evidence suggests that addiction is a brain disease. Three stages of addiction involving changes in specific brain regions have been elucidated.

The Importance of Insight

Decreased insight is a frustrating aspect of many psychiatric disorders. Elucidating the mechanisms underlying insight may lead to better compliance with treatment recommendations.

The Relationship Between Schizophrenia and Dementia

In a recent study, schizophrenia was associated with a higher risk of developing dementia at an earlier age. Co-morbid medical conditions did not account for this elevated risk.

Why Do People With Schizophrenia Die Prematurely?

On average, individuals with schizophrenia die more than 25 years earlier than the general population. Both natural and unnatural causes are responsible for these premature deaths.

Alcohol and Marijuana

Alcohol and marijuana use disorders are common. Some individuals use both drugs simultaneously. With the increased use of both drugs, will it be more dangerous on the roads?

What Is Happening to Middle-Aged White People in the U.S.?

Previously decreasing mortality rates have reversed for 45- to 54-year-old white men and women in the U.S. due in large part to higher suicide rates and more accidental overdoses.

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