By Clayton Simmons, published on May 1, 2009 - last reviewed on June 9, 2016
Fibromyalgia is a mysterious disorder that afflicts up to 12 million Americans, mostly women. Patients who have it report terrible pain throughout the body, but doctors can't find anything physically wrong.
A research meta-analysis, however, suggests that fibromyalgia pain may be treatable using antidepressants. Some doctors suggest that the disorder stems from depression, but these results seem to counter that argument, since antidepressants soothe fibromyalgia pain even at lower doses than those required to treat depression. And the neurological pathways antidepressants affect in fibromyalgia are distinct from those by which they lift spirits, lead author Winfried Haeuser says.
Nondrug treatments are essential to battling fibromyalgia.