Delirium (Treatments)

The goal of treatment is to control or reverse symptoms. Treatment varies with the specific condition causing delirium. Diagnosis and care should take place in a pleasant, comfortable, nonthreatening, physically safe environment. Hospitalization may be required for a short time.

The cause should be identified and treated.

Stopping or changing medications that worsen confusion, or that are not essential to the care of the person, may improve cognitive functioning even before treatment of the underlying disorder. Medications that may exacerbate confusion include alcohol and illegal drugs, anticholinergics, analgesics, cimetidine, central nervous system depressants, lidocaine, and other medications.

Disorders that contribute to confusion should be treated. These may include heart failure, decreased oxygen (hypoxia), high carbon dioxide levels (hypercapnia), thyroid disorders, anemia, nutritional disorders, infections, kidney failure, liver failure, and psychiatric conditions such as depression. Treating medical and psychiatric disorders often greatly improves mental functioning.

Medications may be required to control aggressive or agitated behaviors that are dangerous to the person or to those around them. These are usually given in very low doses, with adjustment as required.

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Medications that may be considered for use include:

Thiamine, sedating medications such as clonazepam or diazepam, serotonin-affecting drugs (trazodone, buspirone), dopamine blockers (such as haloperidol, olanzapine, risperidol, clozapine) and fluoxetine, imipramine, celexa (mood stabilizers).

Some people with delirium may benefit from hearing aids, glasses, or cataract surgery.

Formal psychiatric treatment may be necessary. Behavior modification might be helpful for some people to control unacceptable or dangerous behaviors. This consists of rewarding appropriate or positive behaviors and ignoring inappropriate behaviors (within the bounds of safety). Reality orientation, with repeated reinforcement of environmental and other cues, may help reduce disorientation.

Acute disorders that cause delirium may coexist with chronic disorders that cause dementia. Acute brain syndromes are potentially reversible with treatment of the underlying cause. Delirium often lasts only about one week, although it may take several weeks for cognitive function to return to normal levels. Full recovery is common.

Delirium. Last reviewed 05/16/2008

Source:

  • National Institutes of Health

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