Alzheimer's Disease (Treatments)

Currently, the progression of AD can be slowed, but the disease cannot be cured, and impaired functions cannot be restored.

Treatment focuses on slowing the disease's progression; managing the patient's behavior problems, confusion, and agitation; modifying the home environment; and supporting the family. As symptoms worsen, the disease may take a greater toll on the family than on the patient.

Underlying disorders that contribute to confusion should be identified and treated. Behavior modification may be helpful for some patients in controlling unacceptable or dangerous activity.

For some people in the early or middle stages of the disease, medicines such as Cognex, Aricept, Exelon, or Reminyl may temporarily slow the progression of the disease. Memantine is sometimes used in moderate and severe stages to help patients maintain some daily functions for a little longer. Also, some medications may help control behavioral symptoms such as sleeplessness, agitation, wandering, anxiety, and depression. These treatments are aimed at making the patient more comfortable. It may be necessary to stop any medications that make confusion worse including painkillers, cimetidine, central nervous system depressants, antihistamines, sleeping pills, and others. Never change or stop taking any medicines without first talking to your doctor.

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Research at the National Institute on Aging, the National Institute of Mental Health, and the National Institute of Neurological Disorders and Stroke is exploring possible new options for treating Alzheimer's. For example, a clinical trial is under way to see if anti-inflammatory drugs may ward off symptoms in at-risk people who are currently healthy. Another study is looking at whether statins, traditionally used to combat heart disease, may help Alzheimer's. Other studies are looking at the role of B and E vitamins, estrogen, and gingko biloba. Results are not yet available from these trials. Patients interested in participating in clinical trials should speak to their physicians.

Alzheimer's Disease. Last reviewed 12/05/2007

Sources:

  • National Institute of Mental Health
  • National Institute of Aging (2006). Alzheimers Disease Fact Sheet
  • National Institute of Aging (2007). Understanding Stages and Symptoms of Alzheimer's Disease
  • National Institute of Neurological Disorders and Stroke
  • National Institutes of Health - National Library of Medicine

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