Various spices contain psychoactive chemicals that can alter the function of the brain. The spice nutmeg comes from nutmeg tree, Myristica fragrans, and contains myristicin, which is chemically quite similar to mescaline and amphetamine. Myristicin is also found in parsley and carrots as well but at very low concentrations, so no reason to worry about getting intoxicated at the hors d'oeuvres tray. Typically, one must consume about 30 grams of nutmeg powder-or roughly the contents of an entire container of the product that you could purchase at your local grocery store-to experience its psychoactive effects. Therefore, a single slice of pumpkin pie or a glass of eggnog are unlikely to produce any noticeable effects upon the psyche. Reactions vary considerably, from nothing at all, to euphoria at low doses, to marijuana- and LSD-like experiences at higher doses, with hallucinations that can last up to 48 hours. Chronic use of high doses of nutmeg can produce a reaction similar to psychosis. One other unpleasant side effect of nutmeg is extreme diarrhea caused by the stimulation of sensitive neurons within the intestines. Given this disagreeable side effect, it is surprising that nutmeg has also been claimed to be an aphrodisiac. Perhaps for these reasons, one of my students consumed an entire canister of nutmeg that he had dissolved in some applesauce; the weekend he spent in the bathroom demonstrated why most people never try nutmeg more than once.