In the New York Times science section today (August 31), Weill Cornell Medical College psychiatrist Richard Friedman writes about how illicit drugs like cocaine and methamphetamine may permanently reduce a person's capacity for enjoying life's splendors. These drugs, he notes, activate the brain's reward system by releasing dopamine. However, he observes, the brain then tries to compensate for the drug's presence, and it does so by becoming less sensitive to dopamine. The brain may end up with a "less responsive reward circuit," Friedman writes, which never fully repairs itself even after the drug use stops. The result is that the person may then be condemned to "endure a dulled life."
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