Genius and Madness

Oy! That's depressing...

It is more than a matter of SSRIs not being very effective. There are a lot of tragedies involved in the national consumption of SSRIs.

The Physicians Desk Reference states that SSRI antidepressants and all antidepressants can cause mania, psychosis, abnormal thinking, paranoia, hostility, etc. These side effects can also appear during withdrawal.

Go to www.SSRIstories.com where there are over 3,400 cases, with the full media article available, involving bizarre murders, suicides, school shootings/incidents [51 of these] and murder-suicides - all of which involve SSRI antidepressants like Prozac, Zoloft, Paxil, etc, . The media article usually tells which SSRI antidepressant the perpetrator was taking or had been using.

Read somewhere that the 2-4 week lag could be due to the proposed idea that anti-depressants therapeutic effect is the regeneration of the amygdala, which has been shown to suffer from neuronal death in the depressed.

Many millions of Americans take antidepressants because they don't work.? You make me laugh.

Sincerely,David

While it may be a fact that a placebo replicates the effect of the antidepressants, I think this speaks more to the strength of placebo effect than it does to the effectiveness of the antidepressants. The power of the human brain is nothing short of miraculous. The placebo effect has been proven to be a very powerful healing agent... that cures people! It cures people of physical as well as mental ailments. So, the fact that a placebo can replicate the results of the antidepressants does not mean that the antidepressant are ineffective at all. In fact, because the placebo only replicates a portion of the results proves that antidepressants do have certain agents that work and have an effect beyond that of human thought.

Don't ever be fooled by comparisons with placebos. If a drug can surpass the placebo effect that means it works.

While it may be a fact that a placebo replicates the effect of the antidepressants, I think this speaks more to the strength of placebo effect than it does to the effectiveness of the antidepressants. The power of the human brain is nothing short of miraculous. The placebo effect has been proven to be a very powerful healing agent... that cures people! It cures people of physical as well as mental ailments. So, the fact that a placebo can replicate the results of the antidepressants does not mean that the antidepressant are ineffective at all. In fact, because the placebo only replicates a portion of the results proves that antidepressants do have certain agents that work and have an effect beyond that of human thought.

Don't ever be fooled by comparisons with placebos. If a drug can surpass the placebo effect that means it works.

While it may be a fact that a placebo replicates the effect of the antidepressants, I think this speaks more to the strength of placebo effect than it does to the effectiveness of the antidepressants. The power of the human brain is nothing short of miraculous. The placebo effect has been proven to be a very powerful healing agent... that cures people! It cures people of physical as well as mental ailments. So, the fact that a placebo can replicate the results of the antidepressants does not mean that the antidepressant are ineffective at all. In fact, because the placebo only replicates a portion of the results proves that antidepressants do have certain agents that work and have an effect beyond that of human thought.

Don't ever be fooled by comparisons with placebos. If a drug can surpass the placebo effect that means it works.

yes, placebo is powerful. in fact, it has about a 45% efficacy rate when it comes to moderate depression; 70% efficacy (in some studies) when it comes to mild depression...

and yes again, SSRIs do SLIGHTLY outperform placebo; so I agree, they do "work." But "work" amounts to a difference of about 2 points on the Hamilton Depression Scale. Nothing to get excited about, in other words.

some people, for instance Walter Brown, recommend placebo as a treatment for depression. in principle, not a crazy idea at all.

that belief is essential

I am a psychotherapist in New York City and I worl with clients who have symtoms of anxiety and depression. My experience has been, if the client needs to be stabilized anti depressants are helpful when the psychiatrist finds the medication that suits the client.

There is always a reuptake period where the receptor sites in the brain slowly change their functioning pattern . It doesn't work instantly

I am curiuos, what study(ies) are you citing? How many participants were in it? Was it a longituenal study. I am asking because there are many theaories abiut what works but if the study does not have reliability or utility it's conclusions prove nothing.

www.nycpsychotherapist.org

Pretty interesting site you've got here. Thank you for it. I like such topics and anything that is connected to them. I definitely want to read more on that blog soon.

Hilary Swenson
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