When I was writing my book "Can't Remember What I Forgot," the seminal question that friends and acquaintances asked me was whether doing crossword puzzles was really going to help them avoid Alzheimer's and other kinds of cognitive decline. Now that the book is out, that's the question that journalists are most keen to ask as well. It's easy to understand why people think crosswords are protective: a number of years ago a famous study of nuns was published that showed that those who lived the longest without cognitive impairment were also those who did the crossword puzzle every day. To readers, it looked like cause and effect, but of course it was only a correlation, and correlations don't "prove" anything, though they're provocative. In fact, in this case, the correlation could have come from a different cause altogether: that those nuns who did the crossword puzzle were always more verbally and mentally endowed, which is why they were drawn to the challenge of the puzzle in the first place, and that endowment was what kept them from succumbing to cognitive decline. (This hypothesis was given a boost when it was found, on autopsy, that some of those mentally fit, crossword puzzle playing sisters had some of the physiological signs of Alzheimer's, like plaques in the brain.)
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