All About Addiction

Helping addicts get their lives back.

Hold that needle: Acupuncture for holistic addiction treatment?

Holistic treatments are popular, especially among those that have money, but when it comes to treatments that don't have to go through regulatory approval, it's important to do your research before you buy in. When it comes to acupuncture, opiate withdrawal relief seems to be the only supported use... For now. Read More

False claims

Adi,
Good to see a student taking an interest in an important subject. As a Certified Alcohol and Drug Counselor working in an inpatient subacute acupuncture-based detox program, it would not be ethical for me to recommend only "one" modality to addicted clients I work with. And while clients have told me "wow, acupuncture really helped" (I place high value on reports from my clients on what they are finding to work for them), and while I have seen observed changes in struggling clients after they receive the NADA protocol (their guard comes down, they listen better, they're more receptive, they start to smile, they appear calm and relaxed), I would never tell clients to "just" use acupuncture as the only aspect of their recovery. This would set them up for failure.

NADA trainer and acupuncturist Roger Lore said it best: "If integrative medicine means one person sits in front of a computer and rolls out research abstracts to make a complete picture of medicine, then it will never work. There is a clear need to integrate data from patients and practitioners, not just data from randomized controlled trials using placebos. The fact RCT's have been used only for the last 20 years for drug studies should give us pause."

The study you have based your conclusions on may be one of the most well-funded studies on acupuncture for addictions, but it is not the smartest one. When these researchers recommended, in the end, that acupuncture is "not a stand alone treatment for cocaine addiction," they did not prove much. The multitude of clinics that use the NADA protocol for addictions treatment do "not" use it as a stand alone therapy--therefore this CATS study does not reflect the "real world" of addictions treatment. This CATS study was a Randomized Control Trial, a study design that works well for testing pharmaceuticals, but is not adequate for measuring "evidence" of success an type of addictions treatment, or acupuncture for any condition. The top researchers in both of these fields(both addictions and acupuncture) tell us this.

The conclusions of the CATS study only prove what the 1997 National Institute of Health Consensus Statement on acupuncture already stated: that acupuncture "not" as a stand-alone therapy, but can be beneficial as adjunct to existing therapy. This follows the recommendations for use of acupuncture in addictions treatment by the National Acupuncture Detoxification Association since NADA was founded in 1985. If you--as an aspiring academic in the field of addictions--are interested in understanding not just one RCT out there, but rather the context of research of acupuncture for addictions as well as the many other studies and outcomes data that has been accumulated for decades, refer to "The Guide to Acu Detox Research," (JM Reports, 2007--available for purchase through: http://acudetox.com/bookstore/)

Experience working with recovering addicts has taught me a few things:
1--No one modality cures addiction--not "just" 12-step, not any one thing.
2--Listen to what clients say helps them to stay clean. In spite of the CATS study, I won't tell my cocaine-addicted clients not to seek acupuncture as part of their recovery plan if they find it is helping them. That would not be ethical.

I'll close with an excerpt from a manual designed for addictions clinicians, the Center for Substance Abuse Treatment's (Uncle Sam's) best practice manual for Addiction and Detoxification:
"Acupuncture is one of the more widely used alternative therapies within the context of addictions treatment. It has been used as an adjunct to conventional treatment because it seems to reduce the craving for a variety of substances of abuse and appears to contribute to improved treatment retention rates. In particular, acupuncture has been viewed as an effective adjunct to treatment for alcohol and cocaine disorders, and it also has played an important role in opioid treatment (i.e., methadone maintenance). It is used as an adjunct during maintenance, such as when tapering methadone doses. The ritualistic aspect of the practice of acupuncture as part of a comprehensive treatment program provides a stable, comfortable, and consistent environment in which the client can actively participate. As a result, acupuncture enhances the client’s sense of engagement in the treatment process. This may, in part, account for reported improvements in treatment retention (Boucher et al. 2003). A 1999 CSAT-funded study showed that patients choosing outpatient programs with acupuncture were less likely to relapse in the 6 months following discharge than were patients who had chosen residential programs (Shwartz et al. 1999).

Ear acupuncture detoxification, which was originally developed as an alternative treatment for opioid agonist pharmacotherapy, is now augmenting pharmacotherapy treatment for patients with coexisting cocaine problems (Avants et al. 2000). The advocates of acupuncture have joined with the advocates of opioid agonist pharmacotherapy to create a holistic synthesis. Each has contributed to the success of the other, both clinically and in public perception." (pp124
http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=hssamhsatip&part=A85279)

Avants, S.K., Margolin, A., Holford, T.R., and Kosten, T.R. A randomized controlled trial of auricular acupuncture for cocaine dependence. Archives of Internal Medicine 160(15):2305–2312, 2000. 1993.

Boucher, T.A., Kiesuk, T.J., and Trachtenberg, A.I. Complementary and alternative therapies. In: Graham, A.W., Schultz, T.K., Mayo-Smith, M.F., Ries, R.K., and Wilford, B.B., eds. Principles of Addiction Medicine. 3d ed. Chevy Chase, MD: American Society of Addiction Medicine, 2003. pp. 509–532.

Shwartz, M., Sahz, R., Mulvey, R., and Brannigan, P. Value of acupuncture detoxification programs in a substance abuse treatment system. Journal of Substance Abuse Treatment17(4):305–312, 1999.

Evidence for withdrawal relief but little else... followup to Ryan's comment

Dear Ryan, first of all, thank you for reading and responding. I think debate is an important part of all scientific discovery.

Now, I'd like to address your points one at a time:
RCT's were put in place to control for a placebo effect. Clients, when administered a treatment by a "professional" tend to believe that the treatment will make them better, especially when they pay for it. That belief alone makes patients report improvement in their condition and it's the thing that kept "snake-oil" practitioners in business for years. Additionally, there is nothing that says that RCT's can't use integrated solutions, but these have to be paralleled by control conditions in order to make sure that it's the treatment itself, not just the fact that the patient is being treated, that is making them better. You see changes in patients but so does everyone who works in treatment, how do you know that it's the needle placement that does it if you don't conduct an experiment? By the way, the study I cited didn't use acupuncture as a standalone treatment, it used it in conjunction with counseling AND self-help support meetings.

Regarding the effectiveness in detox services, as you'll no doubt notice, I did mention the apparent utility of acupuncture in relieving relapse symptoms, which would make it a good candidate exactly for detoxification periods.

I did not use a single RCT, I cited three different journal articles, including one RCT and two reviews of a multitude of studies.

Regarding the 1999 study that you cited as showing "that patients choosing outpatient programs with acupuncture were less likely to relapse in the 6 months following discharge than were patients who had chosen residential programs." Self selection into an experiment is an almost assured method of biasing your results - Patients choose what they THINK will work, exacerbating the placebo effect further. This is only showing that people who thought (and paid for) acupuncture would help chose it and were indeed shown to be right. Additionally, since there were no controls here at all (it was an observational study), baseline differences, including income, education, physical health, and more play an additional role in confusing the effects.

Overall, the only positive evidence I keep finding has to do with the use of acupuncture in opiate withdrawal, which I already discussed. Aside from that, the jury seems to be pointing at negative, or at the least VERY mixed, findings (That 2000 Avants study used the same data as the later 2003 report that used an Intent To Treat rather than only completer analysis and found no results). Check out those reviews and another recent one from Margolin in 2003.

Adi

Thanks for the correction

Thanks for the correction about the Margolin study. You're right that it used other modalities. However, RCT's remain substandard for measuring effectiveness of addictions treatment or acupuncture. These are complex processes, requiring more than our standard reductionist approaches for both treatment and research. Reports from patients will continue to play an important role in learning from them what helps them in recovery.

confounding variables

...But just for giggles, a look at the other modalities utilized (or not utilized) as well as potential confounding variables from the CATS that may teach us something about what doesn't help cocaine addicts, and what doesn't reflect real-world NADA-style treatment:
1) participants were "offered" treatment (real world: clients who enroll in real world outpatient treatment programs are "required" to attend groups and counseling)
2) more than 50% attended less than one counseling session per month (real world: 2-3x "weekly" is recommended for outpatient treatment)
3) 40% didn't attend self help (real world: 60 meetings in 60 days would be recommended for an 8 week recovery stint)
4) the NADA protocol was provided in small groups or in individual treatments (real world: large groups are the standard)

Last but not least:
5) cocaine addicts were given cash for attendance (I don't know any treatment program that pays addicts to attend treatment, nor do I know any reason why this would improve outcomes.)

and even with cash in their hands as they headed back to the streets, participants used moderately less cocaine. I'll take it...

Not so fast...

i'm in full agreement that there are confounding variables in all studies, but let's break the options you brought up - I think you'll see that they're likely not as detrimental as suggested. Also, attendance in other treatment was controlled for if I remember correctly.

1) In the real world, addicts are "offered" treatment, even when they're paying clients. If you're involved in treatment you know for a fact that a good portion of patients does NOT attend all sessions and that this is even more true in outpatient settings like the one used here.
2) See above. A good portion of the patients here attended 2-3 weekly sessions and I challenge you to find me an outpatient clinic where all enrolled patients (when you include those who enrolled and never did anything as ITT analyses do) attend 3 meetings a week.
3) 60 meetings in 60 days is a nice recommendation, but again, one that is VERY rarely actually followed. Again, the 40% number tells you that the majority of subject DID attend self-help support meetings.
4) I have no knowledge here, so if you tell me that this could make a real difference, which it might but sounds unlikely, I'll defer to you.
5) In your setting people pay for treatment, which increases their motivation to utilize offered tx, in studies it's unethical to have people pay for the tx, and often in order to increase enrollment you need to offer incentives. I agree that it would be nicer for $$$ not to be a factor.

not-so integrated study=not so real world

The researchers admitted their limitations.

Clients were not into this program. Attendance was poor. Why? Let's look at the options that clients had:
1--one on one counseling... a big turn off
2--acupuncture providers who were instructed not to talk or interact with the clients. That doesn't sound like fun at all. That's not how real world NADA workers operate.

Let's work towards real world outcomes-based research methods for addictions and acupuncture. That is what the CATS study teaches us. That is what addicted clients need.

All research has, and admits to, limitations...

but that doesn't mean that nothing can be learned from it. First of all, let's stop focusing on that single study and look at the other 2 reviews that examined a slew of other ones. The conclusions reached were the same, limitations and all. Acupuncture doesn't seem to prevent relapse over-and-above regular treatment. The only supportive evidence I found was from a small group of Chinese researchers that used no control groups. If that's your preferred method, go ahead and believe them instead.

Now are you really trying to tell me that one-on-one counseling is a negative? The psychologist-practitioners would beg to differ with you here, and their multi-billion dollar a year industry would seem to support the notion that people like therapy.

Look, we're not going to agree here - I'll continue to look at data and you'll continue to argue for your experience and that of your colleagues. I'm okay with that.

follow the money

An even more profitable industry--Big Pharma--would also argue that their products be the front line treatment for addictions. In many places, it is. But that doesn't mean that all people who are addicted like to be put on methadone. Above all, let's not forget the experience of our patients.

Explain to me...

how this is different then you continuously advocating for the specific version of treatment that you make money administering?

We don't prescribe methadone.

We don't prescribe methadone.

Explain to me how to design a placebo control for one-on one counseling/therapy as a stand-alone treatment for any condition.

Comparing to standard treatment

It sounds like the articles you are referencing found acupuncture as good as standard treatment. That's not altogether a bad thing as we have few other alternatives. Many of the (thousands of) clients we work with here in New Mexico prefer to have a non-verbal treatment like acupuncture over counseling, but more commonly people use many different modalities to treat their substance use, acupuncture is one, counseling is one, group therapy is one, medication may be one. In fact, no single treatment has hard eveidence that it "works" long term (or even short term) in substance use treatment. It is a hard condition to crack. The most successful treatments combine several modalities along with consequences - drug courts "work" the best.

Nityamo Lian
Public Health Acupuncture of NM

Misleading Article Title

This article's title is misleading. It should have been more specific. As is, it implies that this article discusses the efficacy of acupuncture treatment for all addictions. However, the primary focus of the article is severe cocaine addiction, with additional discussion about heroin addiction. The specificity of this article is hidden by the sweeping claims of the headline. For some types of addiction or for some addicts, relief from withdrawal symptoms may be enough to kick the habit. Responsible reporting will advance research more than marginally clever headlines.

Misleading?

So because the title didn't specify what specific sort of addictions it is misleading? Where does it say "all" addictions? I would agree if you said that the title wasn't specific enough, but misleading is quite a stretch, in my opinion.
Also, if you're claiming to have evidence of effectiveness of acupuncture for other addictions then I'd be happy to review them. Otherwise, I covered the evidence I found.
I would also love to see the evidence that there is a reliable effective treatment for addiction that only relieves withdrawal symptoms' severity. For some addicts and some addictions almost anything MAY be enough to kick the habit. This article wasn't meant to cover ALL aspects of all addictions, just evidence available for RELIABLE effectiveness of acupuncture. Other articles I've written cover other treatments and offer a more comprehensive view. This isn't a book on addictions, just a single article.
Again, I would welcome any other evidence I missed in reference to your objections.

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Adi Jaffe, Ph.D., is an addiction researcher at UCLA.

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