Selective serotonin reuptake inhibitors (or SSRIs) are a class of antidepressants prescribed for depression and anxiety disorders. They work by increasing the amount of the neurotransmitter serotonin. First developed in the 1970s, allegedly with fewer side effects than their predecessors, they continue to generate controversy. Like most antidepressants, the SSRIs are most effective when used in combination with cognitive behavioral therapy and other talk therapy. 

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