Depression: Who's at Risk?

Question: An article I read in a popular magazine compared risk factors for depression to those for other diseases. I understand how smoking causes lung cancer, but not how losing my job means I was at risk for depression before it even happened.

Answer: A "risk factor" is any element that increases the probability of a disorder occurring. Yes, smoking is a strong risk factor for lung cancer. And in the most global sense, life itself is a risk factor for depression. All people face uncertainty, adversity, loss and other obstacles to well-being. But because all people face life difficulties, why isn't everyone depressed?

What makes some people more vulnerable to depression than others? Genes? Outlook on life? Diet? Income? In fact, all these and more predispose to depression, making people especially vulnerable to the effects of stress and adversity.

No one specific gene causes depression, but there is still vulnerability due to a number of genes. A family history of depression suggests, but does not prove, a genetic vulnerability in the face of serious life stressors. Physical illness poses another biologic risk. Some medications and street drugs can also trigger depression. Gender is also a biological risk factor; being a woman increases the risk for depression through hormonal factors related to the reproductive cycle.

Psychologically, the greatest risk factors are associated with your style of coping, your problem-solving style and your style of thought, especially the way you interpret and react to life experiences. There is a big difference between what actually happens to us in life and the meaning we attach to it. That leads to complex issues of personality, temperament, values that can increase or decrease vulnerability.

Socially speaking, depression often surfaces in the context of relationships. Death of loved ones, romantic and marital breakups, betrayals by friends or authority figures can all significantly increase the risk of depression. Depression is far more likely in relationships that are destructive and painful. On a broader level, the culture also poses a risk. Cultures like ours that deemphasize social belonging have high rates of depression.

Other general risk factors include: previous episodes of depression, a history of sexual abuse, a history of early losses of parents, alcohol or drug abuse, the presence of other serious psychological or physical problems and overwhelming stressors.

A risk factor increases probability; disorder is not a certainty. Identifying the particular vulnerability that made the loss of your job a trigger for your depression would be wise, especially if you wish to reduce the risk of future episodes. Maybe it is a value you hold that says your work is your life, maybe it was losing face or prestige, maybe it was the stress of economic insecurity, or any or all of these in combination with other factors, too. The point is, not everyone loses a job and becomes depressed. What pre-existing thoughts, feelings, values or perceptions paved the way for depression to take hold of you? When you have insight into the answer, you"re well on your way to developing both a plan of therapy and of prevention.

Tags: being a woman, biological risk, breakups, coping skills, depression, effects of stress, face uncertainty, genetic vulnerability, global sense, history of depression, hormonal factors, life diet, life difficulties, life experiences, life stressors, lung cancer, personality, physical illness, popular magazine, reproductive cycle, risk factor, risk factors, sense life, street drugs, stress

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