Stuck with the Old Meds?

Many Brits with bipolar disorder are not taking the newest drugs for their condition, according to recent research. Instead, more are taking older antipsychotic medications--which are cheaper yet come with more unwanted side effects.

By Colin Allen, published on May 01, 2003

Only 12 percent of those studied were taking newer treatments, known as 'atypical' medications. Of the 841 surveyed, just over half reported using older 'typical' medications such as the mood stabilizer lithium. The research also found that 45 percent of those studied went off their medication without first consulting their doctor.

The side effects of typical antipsychotic medications can encourage those with bipolar disorder to quit taking their meds. Of participants taking typical medications, 39 percent said they suffered severe tremors. Also, one quarter experienced some level of sexual dysfunction, such as low-sperm production and impotence.

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Previous research has found that one in five people with bipolar disease who stop taking their medication will commit suicide, according to the Manic Depression Fellowship, which sponsored the study. This is 30 times higher than the general population.

Still, atypical medications have their limitations. While they have fewer side effects--like muscle spasms-- recent studies find that atypicals increase the risk of diabetes. Also, it is unclear if there is an actual improvement in treatment, side effects notwithstanding.

The study was organized by the Manic Depression Fellowship, a charity group in the United Kingdom for bipolar disorder, which is also known as manic depression.

For more on bipolar disorder, click here.