Mind Matters

Cognitive intervention teaches people to change how they monitor the environment.

Your brain getting better on cognitive therapy is not doing the same thing as your brain getting better on drugs. Drugs modulate monoamine neurotransmitters in the brainstem; they have a bottom-up effect. Cognitive therapy works top down on your thinking. It reorganizes the way you interact with your environment. You learn to monitor the environment, to increase attention, which is in the medial frontal areas.

Then, once you are aware of a [negative emotional] stimulus, you recognize its relationship to self—and you let it go by. You focus on your breathing. You don't kick it into working memory and sit and ruminate about it. You turn off your lateral frontal lobes. That's what we see in the pictures. For whatever reason you have mislearned how to respond to certain kinds of stimuli; you have to unlearn it.

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Did your study in any way change what you were thinking about the brain?

Yeah, it did. Drugs don't affect activity in the medial frontal region, whereas cognitive therapy does. If you'd have told this old neurologist that I'd be doing cognitive therapy I'd have said you were mad, but quite frankly, it's very fundamental to what we're seeing.

Tags: adaptation, blood flow, cognitive disorder, coping skills, depression, emotional disorder, emotional experiences, encounter, extreme loss, frontal lobe, having a bad day, helen mayberg, life stressors, major depressive episode, mind, neurologist, neuropsychiatry, overthinking, relapse, research, rotman research institute, term depression, university of toronto

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