Almond Joy

Antioxidants found in nuts and green vegetables such as spinach, broccoli and brussels sprouts are rich in vitamins C and E and may have a protective effect against Alzheimer's disease.

Researchers tracked the diets of 815 people, ages 65 or older, who initially appeared free from symptoms of Alzheimer's. By the end of the study, those whose diets included the most vitamin E experienced 70 percent fewer symptoms of Alzheimer's than did subjects who ate foods with little or no vitamin E.

Vitamin supplements did not appear to augment the possible protective effects derived from food. Martha Clare Morris, Sc.D., an epidemiologist at the Rush Institute for Healthy Aging in Chicago, attributes this to a potential ceiling effect: "A certain amount of vitamin E appeared to be protective, but more didn't necessarily reduce the risk of developing Alzheimer's," says Morris. Nonetheless, many subjects were new to the vitamin supplement and longer-term use might further reduce their risk.

Morris found no significant associations between vitamin C intake and a lower incidence of Alzheimer's, but a large-scale Dutch study, published with Morris's findings in the Journal of the American Medical Association (JAMA), cited potential protective effects for both vitamins C and E.

Scientists have long suspected that the antioxidants in these vitamins slow the neurological degeneration that leads to dementia, but no causal link has been established. In a JAMA editorial that accompanied both studies, researchers warned that the protective effects attributed thus far to a high intake of antioxidants might in fact derive from other nutritional sources.

The U.S. recommended daily allowance (RDA) of vitamin E is 15 milligrams; Americans consume only one-half to three-fourths that amount. Vitamin C intake, however, exceeds the U.S. RDA of 75 milligrams for women and 90 milligrams for men.

Experts recommend replacing animal fat with vegetable fat to augment dietary intake of vitamin E. "Instead of eating the hamburger, have seeds and nuts," says Morris.

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