Sad Facts

D id You Know?

Down and Out

•Even when the means are at hand—say, they are offered an activity that will change their frame of mind—people with low self-esteem are less inclined than those with high self-esteem to break a negative mood.

Memory Risk

•Depression appears to create the risk of developing Alzheimer's disease. Those who have the greatest number of depression symptoms carrying the greatest risk.

His-N-Her Genes

•Studies show that at least to some degree, susceptibility to depression rests on different genes in men and women, notably those that influence resistance to stressful events.

Loss of Nerve

•Stress early in life may create lifelong depression vulnerability. Animal studies show that maternal deprivation can permanently alter production of a nerve cell factor that regulates neuronal growth.

Tags: animal studies, depression symptoms, frame of mind, low self esteem, maternal deprivation, men and women, negative mood, nerve cell, nerve stress, neuronal growth, stressful events, susceptibility

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