When Mental Illness Strikes Children

Think "mentally ill," and an adult probably comes to mind. Butmental illness strikes kids, too. Judith Rapoport, M.D., Chief of Child Psychiatry at the National Institute of Mental Health, is on the front trees of the battle against mental illness among children. Lately, she has found new reasons to hope for better treatment--and someday even prevention--of these life-disrupting disorders.

NANCY K. DESS: Is childhood mental illness more prevalent than historically thought?

JUDITH RAPOPORT: Yes. Up to 11% of children whose parents have no psychiatric diagnosis experience depression, anxiety, autism and so on. With psychiatrically disturbed parents, the numbers are even higher.

NKD: One of your interests is childhood obsessive-compulsive disorder (OCD). What is that?

JR: With both childhood and adult OCD, thoughts and habits run wild and interfere with normal life. Contamination and danger are major themes. A boy may wash his hands 100 times after touching a doorknob. One man felt sure that he had hit someone with his car and drove up and down the road looking for the body.

NKD: Why does OCD exist?

JR: The answer starts with a question: "What's the normal function of the brain system that goes bad?" We speculate that such systems have adaptive evolutionary roles. Contamination concerns may derive from an innate "program" related to "soiling the nest" and controlling grooming behaviors. A flaw in how the brain regulates these behavioral routines results in OCD symptoms.

KD: Besides the genetic component, what else does OCD involve?

JR: Intriguing recent research looks at how childhood OCD might arise from streptococcal infection, which causes an autoimmune response in the brain. Put into social context, the implications are profound: If ritualistic behaviors from an early age were relatively common, they could, over time, be integrated into the culture. This work is generating fascinating new ideas about how infectious agents, neurobiology and culture may jointly shape rituals, ceremonies and other traditions.

KD: Let's turn to childhood onset schizophrenia. What have you learned so far?

JR: First, it is rare, much rarer than OCD or depression. In eight years, we've found 55 eases. Yet it is important because it may give clues as to what's going on in the more common later onset schizophrenia, just as studying childhood diabetes led to breakthroughs in understanding diabetes at all ages. We hope our study will help us find the cause of schizophrenia, perhaps someday enabling us to prevent it. Overall, childhood onset schizophrenia is very similar to severe adult onset schizophrenia. Both are characterized by pervasive, serious disturbances in thought, emotions and behavior. We do see a higher rate of genetic markers with childhood onset. We are working hard in this area and are still looking for people with onset of psychotic symptoms before their 13th birthday, to whom we provide excellent evaluation and hospitalization, as needed.

NKD: What should parents, teachers and concerned others watch for?

JR: With OCD, a change in habits--such as increased bathroom time and chapped hands--can be a clue. With schizophrenia, the child may lose interest in friends and have odd ideas and, later, hallucinate. But since healthy children also can develop new habits or hallucinate, concerned parents should seek out a good evaluation.

NKD: Is there hope for these children?

JR: Yes. New drugs have greatly improved life for many children with various psychiatric disorders. But behavior therapy and family counseling are valuable complements to drug therapy. With OCD, for instance, counseling can reduce problematic avoidant behavior. Social support is important, too: Parents who've become advocates for schizophrenic children have mobilized neighborhoods and schools so that their children can be part of a caring community--something everyone needs.

Adapted by Ph.D.

Nancy K. Dess, Ph.D., is a professor of psychology at Occidental College and senior scientist at the American Psychological Association in Washington, D.C.

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