DHEA: The New Blues Buster?

Years ago, DHEA (dehydroeplandrosterone) wes touted as a "youth hormone" thought to heighten energy and libido. While the jury's still out on that promise, now comes the possibility that DHEA beats the blues.

A study published in the Archives of General Medicine found that 90 mg daily of DHEA significantly reduced the symptoms of major depression in patients with the disorder--even in those who had not responded to traditional treatment.

While low blood levels of DHEA, which the body creates naturally, have been linked to depression, researchers aren't sure how the hormone ups mood. It may be a building block for estrogen and testosterone; which both have mood-altering qualities, or it may boost feel-good brain chemicals like serotonin.

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But don't toss the Prozac yet, warns Owen Wolkowitz, M.D., a psychiatry professor at the University of California at San Francisco, since the long-term risks of DHEA are unknown. Still, he says, "seeing the effects in patients with depression was encouraging."

Tags: blood levels, brain chemicals, depression, DHEA, general medicine, hormones, low blood, major depression, mood, psychiatry professor, treatment, university of california, university of california at san francisco, ups, wes