Learn to Remember

MEMORY

One of the rewards of a good education and a stimulating career is that they initially protect the brain from Alzheimer's disease, according to a new study The downside? When the disease does take its toll, it hits harder than it does in less learned victims.

"The time that [more learned victims] suffer is shorter, so they have more productive time before the disease sets in," says Yaakov Stern, Ph.D., of Columbia University, who presented his findings at the recent annual meeting of the American Academy of Neurology

Stern, a neuropsychologist, followed 177 patients with early Alzheimer's disease, an age-related illness marked by memory loss. Stern asked patients to memorize a 12-word list once a year for four years, giving them six chances to recall the items each time. While people with a lower educational or occupational status declined by about one test point a year, those with more schooling---over eight years of education--and higher status jobs--managerial, business, government or technical careers--showed little memory loss in the first two years and then declined by at least two points per year by the end of the study.

Stern believes that high-achievers have a "cognitive reserve" that protects them against memory loss. Thanks to constant brain stimulation, they are likely to have more efficient ways of processing information. So when Alzheimer's begins to destroy neurons, their brain can make up for the loss by performing tasks differently--but only for so long. "There is a point at which they can't compensate anymore," says Stem. "Then the pathology takes over." At this stage, there are so few neurons left that mental ability plunges dramatically So can people beat Alzheimer's by hitting the books or pulling for a promotion? No such luck, says Stem: "No good prevention study shows that any activity or course will prevent dementia."

Tags: academy of neurology, alzheimer's, american academy of neurology, brain, brain stimulation, business government, columbia university, downside, education, good education, high achievers, Memory, mental ability, neuropsychologist, neuroscience, prevention study, productive time, six chances, technical careers, test point, word list, yaakov stern

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