There's no forgetting ginkgo

Q: There's been a lot of hype about the use of ginkgo to improve memory. Isthere any evidence that it works?

A: Definitely, and for more than just memory. Ginkgo--really an extract of leaves from the ginkgo biloba tree--is one of the herbs I use most commonly in my practice, for conditions ranging from depression and memory loss to impotence. Hundreds of studies have shown that ginkgo has powerful therapeutic effects. One of its most potent compounds, Ginkgolide B, was isolated a decade ago by Harvard scientists.

The herb works in large part by dramatically increasing blood flow to the brain. Chronic low blood flow--in some cases caused by heart disease or a stroke--is a significant factor in the impairment of memory and concentration.

Ginkgo may help slow or prevent the degeneration of memory and other mental skills in another way: laboratory experiments with brain tissue suggest that the herb protects neurons from damage by free radicals of oxygen.

More than 40 clinical studies have shown that ginkgo helps improve circulation in the brain and enhances mental functioning. In one study, ginkgo extract was given to 18 patients who suffered from poor memory and concentration. While their short-term recall did not improve immediately, it did get better with continued use of ginkgo. The herb's impact has been most remarkable in elderly patients suffering the effects of strokes or Alzheimer's disease.

There is some evidence indicating that the herb may also help in treating depression. In one study, 40 middle-aged patients with mild to moderate depression who did not respond to medication were given either ginkgo or a placebo. After four weeks, the severity of depression in the placebo group had declined 10%. In the ginkgo group, it had been reduced by 50%, and after eight weeks, by nearly 70%.

One caution: there is no support for the belief that ginkgo is a socalled "smart drug" that can improve normal memory in healthy people.

PHOTO (COLOR): Ginkgo restores memory to those who have lost it--but it's no "smart drug."

BY DR. RICHARD FIRSHEIN

Tags: alternative medicine, blood flow, brain, brain tissue, depression, elderly patients, ginkgo, laboratory experiments, low blood, Memory, mental functioning, moderate depression, placebo group, poor memory, severity, therapeutic effects, treating depression