Natural born killers?

Questions whether violent criminal behavior is a mental disorder. Research of Adrian Raine, Ph.D., who discovered that the prefrontal cortex, the brain region behind the forehead, was less active in murderers; Further details of the study; Implications for justice--and for rehabilitation.

By PT Staff, published on January 01, 1995

BRAINPrefrontal Cortex

Is violent criminal behavior a mental disorder? A University of Southern California psychologist says yes--and he'll show you brain scans to back up his claim.

Adrian Raine, Ph.D., led a team that compared brain activity in 22 murderers and 22 normal folks. Their tool of choice: the PET scan, an imaging technique that measures the brain's utilization of glucose, its primary fuel. The scans indicate which areas of the brain are active--and which are lying low.

The researchers discovered that the prefrontal cortex, the brain region right behind the forehead, was less active in the murderers. Prefrontal deficiencies have been associated with a variety of behaviors--risk taking, rule breaking, aggression, and impulsivity--that can lead to violence.

But there's a catch. The murderers in the study had all pleaded not guilty by reason of insanity. Might mental illness account for their abnormal PET scans? No, says Raine; insanity is a legal concept, not a medical condition. The variety of mental disorders the killers cited in their insanity pleas do not explain their lower prefrontal activity.

If further studies confirm that murderers' brains are biologically different, does this mean that some of us are natural born killers? Not at all. Raine, who says his own brain scan resembles that of a man who killed 43 people, thinks that biological and environmental factors are both essential components of violent behavior.

But the idea that killers' brains are different has profound implications for justice--and for rehabilitation. Cognitive remediation training has helped brain-injured patients recover lost function. If such therapy is able to help violent offenders beef up their brain to compensate for an underactive prefrontal cortex, the changes might show up on a PET scan. Come parole time, those scans could be far more convincing evidence of rehabilitation than a convict's professed remorse.

PHOTO: Woody Harrelson and Juliet Lewis