And Prozac For All..

"The notion that suffering is good is paternalistic and, at worst, sadistic," says Roose. But even if we take that moralistic, almost religious view, why point our swords only at the dragons marked "take as directed"? Why not apply the same questions and concerns to psychotherapy? "The use of psychotherapy in this country has been grandfathered in," points out Bob Trestman. "It's been accepted already for many years, first in terms of counseling from religious leaders, and more recently in the practice of formal therapy. So that we no longer question either its intrusiveness on who we are or its relative safety."

Does psychotherapy have side effects? Is it intrusive? Does it change the essence of who we are? The answer is yes to all. "If psychotherapy couldn't manipulate or effect change, then it wouldn't work," states Roose. "The idea that therapy isn't intrusive, that we don't alter behavior or control people's thoughts is fundamentally untrue."

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What about side effects? "By definition, if a treatment is powerful enough to work, it's powerful enough to have adverse effects. Every journal on psychotherapy will talk about people who regress in treatment, people who have psychotic reactions, people for whom therapy has caused deterioration rather than progress.

"Still," Roose continues, "because these so-called nonsyndromal disorders are considered to be in the realm of psychology, we don't think there's anything wrong in treating them with psychotherapy. We believe that isn't manipulation while medication is--regardless of outcome."

MANIPULATION VS. CHANGE

Yet what if the brain reacted, readjusted itself in the same way, whether in response to a pill or a therapeutic directive?

Last year, in the Archives of General Psychiatry, a research team headed by UCLA's Lewis Baxter, M.D., reported a study of two groups suffering from obsessive-compulsive disorder (recurrent, un-thoughts accompanied by ritualized acts, such as excessive hand-washing). In treatment, one group was given Prozac with no formal therapy, the other behavior therapy, in the form of exercises designed to prevent their compulsiveness, with no drugs. After 10 weeks, scans of their brains were compared with those taken at the beginning of treatment.

Approximately two-thirds of each group improved. More important, for those who did improve, rates of glucose metabolism (an indicator of brain activity) decreased in exactly the same areas of the brain, in statistically similar amounts, regardless of treatment. The behavioral techniques actually altered brain function-and did so no differently, no less intrusively, than Prozac.

"Some may wonder," writes Baxter et al, "how behavior therapy could produce brain-function changes similar to drugs. [But] the possibility of both having the same neural effects is not as farfetched as it might seem."

The brain is the organ of the mind, and its function affects personality. So how far do we go in treating its disorders and distresses, its syndromes and its character flaws? By all accounts, the resounding answer seems to be: as far as it is safe to go. The unanimous opinion among professionals is that more information is needed.

Yet what about the concern that we are entering an age when even the slightest wrinkle in character can be defined as a "disorder." Will we become a Prozac nation? Hardly, thinks Robert Millman, who does not believe the whole of society is going to become dependent upon these drugs. The reason? Evolution, which, over the course of time, has created in us the brain functions that dictate the way we deal with thoughts and emotions. That intricate interplay, he offers, is way beyond the primitive effects of any of these drugs.

"The system is so refined," believes Millman, "and drugs are so primitive, that one can never really replace the other. With drugs, you're always giving away more than you're getting--if you're not really debilitated. You're giving away sensitivity, receptivity, some capacity for pleasure. But it's a reasonable trade-off if you're in pain."

The only question, then, is for what degree of pain do we seek medical treatment. And, as Bob Trestman puts it, where will it end?

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