Evidence is accumulating that biological factors influence the development of the maladaptive behavioral patterns that constitute personality disorders. From a study of 175 pairs of twins, led by psychiatrist W. John Livesley, M.D., of the University of British Columbia, now comes a clear picture of the heritability of distinct aspects of personality pathology. Several different genetic factors seem to be at play, Livesley reports in the American Journal of Psychiatry (Vol. 150,No. 12). Although most personality disorders have a hefty genetic component, specific environmental factors also have a substantial effect. Genetic vulnerability, it appears, influences the responses we make to adverse environmental circumstances.
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